
Clog-free Filters. For Bioreactors.

We’re building the world’s first inertial microfluidic perfusion filter for bioreactors that removes dead cells, reduces impurities, and keeps yield steady for weeks.
“We lose yield in membrane filters — this could be huge.” – MNC R&D Lead. “Dead cell removal during perfusion? Game-changing.” – Biotech Stakeholder. “We’re always looking for clean, scalable alternatives.” – CDMO Director
Clogging Kills Continuity
Membrane filters foul during runs, causing interruptions, yield loss, and emergency cleanups.
What’s Going Wrong with Traditional Filtration?
Impurities Compromise Safety
Residual Host Cell Proteins (HCPs) can escape membranes, reducing product purity and risking downstream compliance.
Downtime Costs Millions
Every cleaning cycle, membrane replacement, or run stoppage bleeds revenue — especially in high-throughput lines.


1
Clog-Free Operation
Run for weeks without a single stoppage.
Engineered with advanced microfluidics, CelltoMix eliminates the risk of clogging — even during prolonged use. This ensures consistent performance and a stable yield over time, reducing downtime and maintenance compared to traditional filters.

2
Removes Dead Cells in Real Time
Cleaner product. Simpler downstream.
Removes 25–50% of dead cells during perfusion, cutting HCPs before they reach purification.

3
Boosts Viability by 2–4%
Stronger culture. Higher return.
Higher live cell density = higher product yield.
Proven +14% titer vs membrane ATF systems.

4
Plug-and-Play + GMP-Ready
Bioreactor ready from Day 1.
Works from 2L to 2000L. No installation. Fully disposable.
OPC-compatible. Integrates with Segflow & ProSIA.

At CelltoMix, we are redefining bioprocessing through next-generation microfluidic technology. Founded by leading scientists and engineers, our mission is to solve the industry’s toughest filtration challenges — starting with clog-free, high-yield microfilters.
With a science-first approach and over two decades of international research experience behind our core team, we’re building tools that increase cell culture productivity, reduce operational downtime, and optimize bioreactor performance.
We believe innovation in life sciences begins at the microscopic level — and that’s exactly where we thrive.

Dr. Shireen Goh
Co-Founder
Dr. Shireen Goh is scientific co-founder of Celltomix and Associate Professor at SUTD, specializing in microfluidics and biomanufacturing with technologies licensed to industry, including Erbi Biosystems (acquired by Merck in 2022).

Dr. Danny van Noort
Co-Founder
Dr. Danny van Noort is an internationally recognized researcher with 25+ years of experience in physics, microtechnology, and biomedical engineering. He specializes in biosensors, DNA computers, organ-on-chips, and 3D cell models, with numerous publications and global lectures.

Leo Siang Kwong
Co-Founder
Leo Siang Kwong is an expert in digital transformation and automation, with 25+ years of experience in technology and engineering. A certified PMP and ScrumMaster, he specializes in leading large-scale digital initiatives, smart manufacturing, and ERP solutions, translating business vision into scalable innovation.